Programs > Brochure
Budapest, Hungary (Outgoing Program)
|Partner Institution/Organization Homepage:||Click to visit|
|Restrictions:||Princeton applicants only|
|Dept Offering Program:||IIP, International Internship Program (IIP)||Program Type:||Internship|
|Language Prerequisite:||No||Program Features:||Lab Based Work, Research|
|Degree Level:||2 First year Ugrad, 3 Sophomore, 4 Junior||Time Away:||Summer|
|Housing options:||Student Responsibilty with support from IIP and/or Host Organization||Program Group:||International Internship Program|
About: Founded in 1769, Semmelweis University, Hungary’s oldest medical school offers courses in medicine, dentistry, pharmacy, health sciences, health management, as well as physical education and sport sciences. This University is widely recognized as one of Europe’s leading centers of medicine and health sciences, combining innovation and a time-tested tradition in three main areas: education, research, and health care. It is one of the largest health care institutions in Hungary, covering approximately six percent of the nation’s health care needs.
Intern Responsibilities: IIP internships at the University Medical School provide access to different laboratories at the university to learn about ongoing research, help in the experiments and carry out mini-projects, such as data collection and/or analysis, literature search, help in drafting scientific papers. Interns will be matched with professors and researchers (mentors), based on their interest and availability of mentors. It is anticipated that the interns can spend time in at least four different labs on their interest. Research areas available for this IIP internship include, but not limited to biology, biophysics, chemistry, biochemistry, physiology, pathophysiology, anatomy, nanomedicine. After successful completion of the program, students will be awarded a dedicated certificate of achievement.
Qualifications: Candidates with interests in biology and/or basic medical sciences are encouraged to apply.
Previous work experiences (in the words of past IIP interns): Intern#1: Read laboratory research articles; Helped analyze experimental data; Ran trials for liposomal characterization experiment; Learned to use atomic force microscopy technology. Intern #2: The main project I am working on deals with fibrin which is a protein involved in blood clotting. We saw how fibrin forms under different conditions, varying the concentrations of calcium and sodium. I learned to take AFM images using a machine called a Cypher to look closely at how the fibrin had formed. I also performed a gel electrophoresis on fibrin and other proteins that are a part of the blood clotting process, like factor VIII. I also worked on minor projects like sub culturing cells and performing PCR reactions. Intern #3: Using nanotechnology to stretch the protein titin, both full length titin and some single domains of titin, in order to study the structure of the protein and the forces needed to unfold it's structure. I have also assisted with a smaller project measuring the viscoelasticity of the protein fibrin as it forms blood clots. In addition, I worked on Next Generation Sequencing: creating genomic libraries of DNA samples using PCR. Intern #4: We studied predominantly the effect of temperature on cochleate formation, but also studied best practices for formation and disintegration. Day to day, we performed various experiments and record the data to hopefully come to some conclusions about the properties of cochleate. The goal of the research is to one day understand cochleate well enough to utilize them as drug delivery devices. I also spent a week in Miskolc shadowing a lab that analyzes genetic information, and, I was able to assist and shadow different colleagues at Semmelweis University from the Nanomedical Department to the Pediatric clinic. Intern #5: Worked alternatively on several different projects with different researchers - including the von Willebrand factor (involved in blood clotting) and its affinity for bonding with collagen at different concentrations, using optic tweezers to observe the structural mechanics of titin (a large muscle protein in the body), and qualitatively analyzing kidneys with varying levels of fibrosis in experimental rat populations. I worked on different projects on different days so there's a lot of variety in what I'm learning. I ran a lot of basic lab procedures that I learned in basic science classes at Princeton, and for the procedures I hadn't learned yet, the researchers guided me through how to do them and then let me do them independently. I learned a lot more about physics and biophysics than I thought I would, since many of the projects are at the very interesting biophysics institute close to the main building, but I found these projects fascinating (particularly the optic tweezers project, which involves stabilizing one end of the protein in with a laser and designing flow cells to attach the protein to the right place, as well as deeply familiarizing myself with the atomic force microscope on several different projects).
View a PowerPoint presentations by past IIP interns:
Karetnick, Morgan, Semmelweis University, Hungary.pptx
Szebeni, Miklos, Semmelweis, Hungary.pptx
Semmelweis University. Hungary, Geil, Gianna.pdf
Semmelweis, Hungary, Mulligan, Kathleen.pdf
Semmelweis, Hungary, Szebeni, Miklos.pdf
This internship is offered in partnership with the Program in Global Health and Health Policy and can be used by GHP juniors for completion of the GHP Summer Research Requirement (please check the appropriate box on your application).
|Dates / Deadlines:|